Of the house, that is. Aim for a few hours out every day, says Dr. Vittone. Being in the same place too long, particularly if you're alone, is a breeding ground for depressive thoughts and symptoms. Visit the library, go shopping, see a movie. Stimulation is important for people with depression, he says. Researchers speculate that stimulation keeps the brain's feel-good neurotransmitters, such as serotonin, flowing.