Safe and effective, taking acetaminophen on a daily basis is the standard recommendation for minor arthritis pain. "Tylenol is the mainstay of operation," says Dr. Fiechtner. "It doesn't work for everybody, obviously, but it seems to work well if you don't take too much of it."
"The problem with taking many over-the-counter pain relievers every day is that they increase your risk of developing stomach ulcers," says Dr. Fiechtner. He recommends acetaminophen because unlike aspirin, ibuprofen, and naproxen (Aleve), which can all cause ulcers, acetaminophen is not associated with stomach problems.